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1.
Indian Pediatr ; 1992 Sep; 29(9): 1133-7
Article in English | IMSEAR | ID: sea-11224

ABSTRACT

One hundred and four cases of osteoarticular tuberculosis were studied. There were 74 boys (71.2%) and 30 girls (28.8%). The mean age at the onset of symptoms was 7.3 years, ranging from 9 months to 18 years. Seventy four cases (71%) reported 3 months after onset of symptoms. The spine was the commonest site involved (43%) followed by hip (14.9%) and knee joints (10.3%). Evidence of active or inactive pulmonary tuberculosis was found in 16.2%. All cases were treated by three drug regimen of rifampicin, isoniazid and ethambutol; rifampicin was discontinued after 6 months, ethambutol after 12-14 months. In 12 cases (11.5%) isoniazid was continued for 18 months. Along with chemotherapy suitable braces, splints, tractions, exercises and other form of physical therapy produced satisfactory results. Seventy eight patients (75%) showed clinical and radiological improvement with one year of treatment. The follow up period ranged between 4 months to 24 months with an average of 17 months. Children because of capacity to grow, showed progressive deformity in knee in 3 cases (2.8%), hip in 98 cases (8.6%), shortening of limbs in 14 cases (13.4%) and kyphosis in 13 cases (12.5%).


Subject(s)
Adolescent , Antitubercular Agents/therapeutic use , Child , Child, Preschool , Drug Therapy, Combination , Female , Follow-Up Studies , Humans , Infant , Male , Retrospective Studies , Tuberculosis, Osteoarticular/drug therapy , Tuberculosis, Spinal/drug therapy
2.
Indian J Exp Biol ; 1976 Mar; 14(2): 189-90
Article in English | IMSEAR | ID: sea-57227
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